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Use of Potent Psilocybe Mushroom to Cure PTSD: Tips to Know

Approximately 5% of the Canadian population has received a definitive diagnosis of post-traumatic stress disorder1 (PTSD). Yet an additional 8% meet the criteria for probable PTSD based on recent symptoms. These symptoms can impact an individual’s well-being and overall quality of life.

Patients opt for the conventional approach, while others seek a more proactive role in their healthcare journey by integrating alternative methods alongside traditional protocols. Some individuals have explored unconventional avenues, including using the most potent Psilocybe mushroom in their experimentation.

If you want to attempt an alternative treatment like shrooms, learn more about how magic mushrooms are becoming popular among some patients.

Key Takeaways:

  • PTSD is a mental issue that can affect the daily life of the patient.
  • Shrooms and other classic psychedelics diminish the amygdala’s activity, a factor that could help PTSD patients. 
  • Multiple strains of Psilocybe cubensis can offer a potent experience.

Exploring PTSD: Symptoms and Treatment

PTSD is a mental health issue stemming from exposure to a profoundly distressing event. Indications may encompass recurrent flashbacks, distressing nightmares, heightened anxiety, and persistent intrusive thoughts related to the traumatic incident.

Individuals undergoing traumatic experiences commonly face transient challenges in adapting and coping. In the event that symptoms escalate, persist over extended durations, or significantly hinder daily functioning, doctors will consider PTSD treatment.


Recurrent, unpleasant recollections of the horrific eventReliving a distressing incident as if it were happening again.Having disturbing dreams or nightmares regarding the tragic incidentTrying to avoid thinking about or discussing the heinous occurrence Avoiding places, activities, or people that trigger you of the eventNegative feelings about yourself, other people, or the worldMaintaining close relationships is difficult.DisconnectionLack of interest Lack of positive emotionsFeeling emotionally numbBeing quickly startled or terrifiedAlways being on the lookout for riskSelf-destructive behaviourProblems sleeping and concentratingIrritability, rage, or aggressive behaviourOverwhelming feelings of guilt or shame


Treatment for PTSD aims to empower individuals to reclaim control over their lives. The central therapeutic approach involves psychotherapy2, complemented by the potential inclusion of medication. The integration of these modalities serves to enhance symptom alleviation by:

  1. Equipping individuals with skills to manage and address their symptoms effectively.
  2. Facilitating a positive shift in one’s perspective towards oneself, others, and the world.
  3. Instilling coping mechanisms for potential reemergence of symptoms.
  4. Addressing concurrent issues commonly associated with traumatic experiences, such as depression, anxiety, and substance misuse.

Studies on How the Most Potent Magic Mushroom Impacts PTSD Treatment

The limitations embedded within current therapeutic approaches emphasize the need to explore innovative interventions for addressing PTSD. 

Inspired by anecdotal reports from individuals who have experimented with psilocybin-containing mushrooms and promising preliminary research findings, certain scholars have devoted their attention to investigating the feasibility of incorporating such substances into PTSD treatment strategies.

University of South Florida, 2013

Psilocybin promotes neurogenesis by fostering the proliferation and restoration of brain cells within the hippocampus3—an integral hub for both emotion and memory functions. In a recent study, the mice administered psilocybin exhibited superior resilience in overcoming fear conditioning compared to their counterparts who received a placebo. 

This research substantiates the notion that psilocybin holds the potential to disrupt the debilitating cycles associated with PTSD in patients.

Cureus, 2022

Psilocybin and other psychedelics function by engaging with the serotonin4 receptor. These chemicals can treat depression, anxiety, and alcoholism.

These substances can diminish the amygdala5‘s reactivity during emotional processing, a factor that could help PTSD patients who often exhibit heightened amygdala activation. 

Apart from these effects, classical psychedelics may contribute to PTSD management through additional acute outcomes.

  • Heightened emotional empathy
  • Increased insightfulness
  • Enhanced acceptance
  • Transformative emotional experiences

Even though there hasn’t been much research on psilocybin’s impact on PTSD, it’s evident that its good effects extend beyond only resolving PTSD. The study of its effect on co-occurring mental health problems connected with PTSD indicates interesting therapy options.

What is/are the Most Potent Shrooms?

The preeminent magic mushroom in terms of potency is Psilocybe azurescens. However, due to its limited online availability and relatively high cost, Psilocybe cubensis emerges as the foremost choice.

P. cubensis is available in diverse strains, each exhibiting distinct levels of psilocybin content. Presented here are some of the most potent strains accessible for purchase through online platforms.

Penis Envy Cubensis

Phallic shapeBulbous capShort and fatLight tan to a darker brownVery Potent0.94%

Albino Penis Envy

Striking white hueDomed capThick stemsAbove Average0.93%

Blue Meanies

Light gray to off-whiteCaps are bell shape, appearing convexStems are 12cm (height) and are 2-4mm (thick), slim and long with a blue tingeAverage0.67%


White stems that are thick and can turn blue when softly touched.Enormous golden-brown caps resembling domes from St. Basil’s Cathedral in RussiaAbove Average1.12%


Clustering of mycelial bodies in the shape of a brain It is also incapable of spreading spores or producing a complete fruiting body.Above Average0.76%


While research on the effects of magic mushrooms on PTSD is currently limited, emerging theories regarding its neural mechanisms suggest encouraging therapeutic potential. 

More and more evidence suggests its efficacy in addressing concurrent mental health concerns such as depression and anxiety. 

As scientific exploration advances in the application of psilocybin, an increasing number of individuals undergoing PTSD treatment may discover complementary solutions for their condition. Visit zoomiescanada.ca to learn more.

Frequently Asked Questions

What is the most PSM?

Psilocybe azurescens, renowned as the preeminent magic mushroom globally, certainly delivers a potent experience—provided you can locate it. It grows in the Columbia River along the western coast of the United States.

Psilocybe azurescens component:

  • 1.8% psilocybin
  • 0.5% psilocin. 

Locating this particular Psilocybe mushroom proves to be a challenging task. Your best course of action would be to buy Psilocybe cubensis online.

How does it feel when using shrooms?

EuphoriaA profound and heightened state of joy or happiness. Common indicators include spontaneous and uncontrolled bursts of laughter without apparent cause. 
A peculiar sensation of weightlessness and a pervasive atmosphere of positivity.
PeacefulnessThe experience is characterized by emotional detachment, effectively dampening various feelings and acting as a barrier against unwelcome thoughts within one’s consciousness.
Hallucination – Visual and AuditoryIt possesses the capability to modify one’s auditory perception subtly. For instance, engaging with hard rock music transforms the experience into a soothing, gentle sound that brings a sense of comfort to your senses. 
It has the potential to influence one’s perception of objects. For instance, contemplate observing your wall clock, and unexpectedly, it undergoes a transformative process, resembling the liquefaction of an ice cream cone with a slightly distorted form. 

How to take strong Psilocybe mushrooms?

  1. Find yourself in a secure and familiar environment, surrounded by individuals you can rely on. 
  2. Ensure that water, fruit juice, herbal teas, and a light snack are readily available. The duration of effects spans 3-6 hours. Consuming sustenance during this period is advisable, regardless of your hunger level.
  3. Refrain from consuming any food for a minimum of three hours before ingesting the mushrooms. This practice enhances the expeditious absorption of psilocybin into your system.
  4. Mixing these substances with additional compounds may lead to an undesirable psychoactive experience.

Note: Individuals experiencing a suboptimal mood or grappling with depressive tendencies may be more susceptible to an adverse encounter in such instances.

What is the proper dosage when consuming potent mushrooms?

Determining an optimal dosage is subjective, as the appropriate amount varies based on individual proficiency and desired outcomes. 

Microdose0.05–0.5gEffects are not noticeableStress reduction, improved mood, increased creativity, increased vitality, and openness
Beginner Dose0.5–1gA little bit euphoric
Mild Dose1-1.5gMild to moderate visualsEuphoriaEnhanced creativity
Medium Dose2-3.5gIntense euphoriaStrong philosophical insightsIntense emotions
Full Blown Dose4-5g+Strong visualsEgo dissolutionOne with nature

Can a beginner use potent mushrooms?

It is not advisable for a beginner to use potent mushrooms without a thorough understanding of their potential effects and risks. Novice users may lack the experience needed to navigate the intensity of these substances, which can lead to overwhelming or challenging experiences.

Individuals new to the consumption of potent mushrooms need to educate themselves about the specific type they are considering. Having a supportive and knowledgeable guide or mentor can significantly enhance the safety and positive outcomes for beginners.

  1. Yehuda, Rachel, et al. “Post-traumatic stress disorder.” Nature reviews Disease primers 1.1 (2015): 1-22. ↩︎
  2. Lambert, Michael J., Allen E. Bergin, and S. L. Garfield. “The effectiveness of psychotherapy.” Encyclopedia of psychotherapy 1 (1994): 709-714. ↩︎
  3. Douglas, Robert J. “The hippocampus and behavior.” Psychological bulletin 67.6 (1967): 416. ↩︎
  4. Mohammad‐Zadeh, L. F., L. Moses, and S. M. Gwaltney‐Brant. “Serotonin: a review.” Journal of veterinary pharmacology and therapeutics 31.3 (2008): 187-199. ↩︎
  5. LeDoux, Joseph. “The amygdala.” Current biology 17.20 (2007): R868-R874. ↩︎

Last Updated on by Sanjana


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